Yes, with the following recommendations:
Never unplug any eSATA, 1394, or USB device that is being actively accessed by the operating system (such as during a file copy).
- Unplugging a device while it is being used may result in a system crash and the loss of the ability to recover the data already written to the drive.
- For Macintosh – If you want to unplug an External Drive you must first drag the mounted drive icon to the trash to dismount it. After the drive is dismounted then it can be unplugged.
For Windows – If you wish to disconnect an External Drive, you must use the “Safely Remove” or “Unplug and Eject Hardware” utility located in the Windows Task Bar ( identified by the Green Arrow Icon located close to the clock on your desktop).